The cast of hit TV medical drama Grey's Anatomy has been given a huge pay boost.

The show's star, bride-to-be Ellen Pompeo, has closed a new deal that will earn her almost $200,000 per-episode, according to trade paper The Hollywood Reporter, while castmates Chandra Wilson and James Pickens Jr have secured pay hikes to $125,000.

Producers are close to securing similar deals with castmembers Justin Chambers and T.R. Knight.

The pay increases come a week after details of a salary dispute between ABC bosses and Grey's Anatomy star Katherine Heigl were leaked to the press.

Heigl, Sandra Oh, Isaiah Washington and Patrick Dempsey are among those still negotiating new deals.